Motesanib inhibits Kit mutations associated with gastrointestinal stromal tumors

Motesanib inhibits Kit mutations associated with gastrointestinal stromal tumors

<p>Abstract</p> <p>Background</p> <p>Activating mutations in Kit receptor tyrosine kinase or the related platelet-derived growth factor receptor (PDGFR) play an important role in the pathogenesis of gastrointestinal stromal tumors (GIST).</p> <p>Methods</...

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Bibliographic Details
Main Authors:	Tasker Andrew S, Manoukian Raffi, Juan Todd, Baron Will, Bush Tammy L, Baher Angelo, Renshaw-Gegg Lisa, Caenepeel Sean, Polverino Anthony, Hughes Paul E
Format:	Article
Language:	English
Published:	BMC 2010-07-01
Series:	Journal of Experimental & Clinical Cancer Research
Online Access:	http://www.jeccr.com/content/29/1/96

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