Adipocyte-Based Cell Therapy in Oncology: The Role of Cancer-Associated Adipocytes and Their Reinterpretation as Delivery Platforms

Cancer-associated adipocytes have functional roles in tumor development through secreted adipocyte-derived factors and exosomes and also through metabolic symbiosis, where the malignant cells take up the lactate, fatty acids and glutamine produced by the neighboring adipocytes. Recent research has d...

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Bibliographic Details
Main Authors: Raluca Munteanu, Anca Onaciu, Cristian Moldovan, Alina-Andreea Zimta, Diana Gulei, Angelo V. Paradiso, Vladimir Lazar, Ioana Berindan-Neagoe
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:Pharmaceutics
Subjects:
Online Access:https://www.mdpi.com/1999-4923/12/5/402