Spatiotemporal changes in the distribution of LHFPL5 in mice cochlear hair bundles during development and in the absence of PCDH15.
Mechanosensory transduction by vertebrate hair cells depends on a protein complex at the tips of shorter stereocilia associated with mechanoelectrical transduction channels activated by tip links in the hair bundle. In mammalian hair cells, this complex includes transmembrane channel-like protein su...
Main Authors: | Shanthini Mahendrasingam, Robert Fettiplace, Kumar N Alagramam, Ellen Cross, David N Furness |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2017-01-01
|
Series: | PLoS ONE |
Online Access: | https://doi.org/10.1371/journal.pone.0185285 |
Similar Items
-
The lhfpl5 Ohnologs lhfpl5a and lhfpl5b Are Required for Mechanotransduction in Distinct Populations of Sensory Hair Cells in Zebrafish
by: Timothy Erickson, et al.
Published: (2020-01-01) -
Optimal electrical properties of outer hair cells ensure cochlear amplification.
by: Jong-Hoon Nam, et al.
Published: (2012-01-01) -
Structure of mouse protocadherin 15 of the stereocilia tip link in complex with LHFPL5
by: Jingpeng Ge, et al.
Published: (2018-08-01) -
Hair bundles of cochlear outer hair cells are shaped to minimize their fluid-dynamic resistance
by: Nikola Ciganović, et al.
Published: (2017-06-01) -
Studies on the developmental biology of Trilocularia acanthiaevulgaris (Cestoda, Tetraphyllidea)
by: Mahendrasingam, Shanthini
Published: (1989)