Methods for guantificative assessment of insulin resistance

The article delineates the definition of concept of insulin resistance as well as the factors that determine tissue insulin sensitivity; defines the conception of «insulin resistance syndrome» (metabolic syndrome), its criteria and diseases that it accompanies. It is pointed that the golden standard...

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Bibliographic Details
Format: Article
Language:English
Published: Endocrinology Research Centre 2009-06-01
Series:Ожирение и метаболизм
Subjects:
Online Access:https://endojournals.ru/index.php/omet/article/view/5313
Description
Summary:The article delineates the definition of concept of insulin resistance as well as the factors that determine tissue insulin sensitivity; defines the conception of «insulin resistance syndrome» (metabolic syndrome), its criteria and diseases that it accompanies. It is pointed that the golden standard for quantitative assessment of insulin action is hyperinsulinemic euglycemic clamp. Different indexes for indirect measurement of insulin resistance and possibilities of use of mathematical models for this matter are discussed.
ISSN:2071-8713
2306-5524