Long-Lasting, Antinociceptive Effects of pH-Sensitive Niosomes Loaded with Ibuprofen in Acute and Chronic Models of Pain

Long-Lasting, Antinociceptive Effects of pH-Sensitive Niosomes Loaded with Ibuprofen in Acute and Chronic Models of Pain

Ibuprofen is one of the non-steroidal anti-inflammatory drugs (NSAIDs) widely used to treat pain conditions. NSAIDs encounter several obstacles to passing across biological membranes. To overcome these constraints, we decided to study the effects of a new pH-sensitive formulation of niosomes contain...

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Bibliographic Details
Main Authors: Francesca Marzoli, Carlotta Marianecci, Federica Rinaldi, Daniele Passeri, Marco Rossi, Paola Minosi, Maria Carafa, Stefano Pieretti
Format: Article
Language:English
Published: MDPI AG 2019-02-01
Series:Pharmaceutics
Subjects:
Ibuprofen
pH-sensitive niosomes
Pain
Analgesia
NSAIDs
Online Access:https://www.mdpi.com/1999-4923/11/2/62

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