TGF-β1 and serum both stimulate contraction but differentially affect apoptosis in 3D collagen gels

TGF-β1 and serum both stimulate contraction but differentially affect apoptosis in 3D collagen gels

<p>Abstract</p> <p>Apoptosis of fibroblasts may be key for the removal of cells following repair processes. Contraction of three-dimensional collagen gels is a model of wound healing and remodeling. Here two potent inducers of contraction, TGF-β1 and fetal calf serum (FCS) were eva...

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Bibliographic Details
Main Authors: Zhu Yun, Fang Qiuhong, Abe Shinji, Wen Fu-Qiang, Kohyama Tadashi, Kim Hui, Liu Xiangde, Kobayashi Tetsu, Spurzem John R, Bitterman Peter, Rennard Stephen I
Format: Article
Language:English
Published: BMC 2005-12-01
Series:Respiratory Research
Subjects:
transforming growth factor-beta
apoptosis
gel contraction
fibrosis
wound repair
Online Access:http://respiratory-research.com/content/6/1/141

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