Pannexin-1 Deficiency Decreases Epileptic Activity in Mice

Pannexin-1 Deficiency Decreases Epileptic Activity in Mice

Objective<i>: </i>Pannexin-1 (Panx1) is suspected of having a critical role in modulating neuronal excitability and acute neurological insults. Herein, we assess the changes in behavioral and electrophysiological markers of excitability associated with Panx1 via three distinct models of...

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Bibliographic Details
Main Authors: Mark S. Aquilino, Paige Whyte-Fagundes, Mark K. Lukewich, Liang Zhang, Berj L. Bardakjian, Georg R. Zoidl, Peter L. Carlen
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:International Journal of Molecular Sciences
Subjects:
panx1
seizure
epilepsy
PTZ
4-AP
kindling
Online Access:https://www.mdpi.com/1422-0067/21/20/7510

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