Radical Chemoradiotherapy for Urethral Squamous Cell Carcinoma: Two Case Reports and a Review of the Literature

Radical Chemoradiotherapy for Urethral Squamous Cell Carcinoma: Two Case Reports and a Review of the Literature

Primary urethral squamous cell carcinoma is rare. Its management is particularly challenging owing to the paucity of evidence from randomised trials to inform practice. We report two male and female cases of squamous cell carcinoma of the urethra, which were treated with concomitant cisplatin and ra...

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Main Authors: H. Coop, L. Pettit, C. Boon, P. Ramachandra
Format: Article
Language:English
Published: Hindawi Limited 2013-01-01
Series:Case Reports in Urology
Online Access:http://dx.doi.org/10.1155/2013/194690
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spelling doaj-89365f4243ab428fb6a8807c0bd42f2f2020-11-25T00:13:30ZengHindawi LimitedCase Reports in Urology2090-696X2090-69782013-01-01201310.1155/2013/194690194690Radical Chemoradiotherapy for Urethral Squamous Cell Carcinoma: Two Case Reports and a Review of the LiteratureH. Coop0L. Pettit1C. Boon2P. Ramachandra3Deansley Centre, Royal Wolverhampton Hospital, Wednesfield Road, Wolverhampton WV10 0QP, UKDeansley Centre, Royal Wolverhampton Hospital, Wednesfield Road, Wolverhampton WV10 0QP, UKDeansley Centre, Royal Wolverhampton Hospital, Wednesfield Road, Wolverhampton WV10 0QP, UKDeansley Centre, Royal Wolverhampton Hospital, Wednesfield Road, Wolverhampton WV10 0QP, UKPrimary urethral squamous cell carcinoma is rare. Its management is particularly challenging owing to the paucity of evidence from randomised trials to inform practice. We report two male and female cases of squamous cell carcinoma of the urethra, which were treated with concomitant cisplatin and radiotherapy. These cases add to the body of case reports that have shown benefit for concomitant chemoradiotherapy in urethral squamous cell carcinoma. They also illustrate that single agent chemotherapy, namely, cisplatin, may be used successfully with limited toxicities.http://dx.doi.org/10.1155/2013/194690
collection DOAJ
language English
format Article
sources DOAJ
author H. Coop
L. Pettit
C. Boon
P. Ramachandra
spellingShingle H. Coop
L. Pettit
C. Boon
P. Ramachandra
Radical Chemoradiotherapy for Urethral Squamous Cell Carcinoma: Two Case Reports and a Review of the Literature
Case Reports in Urology
author_facet H. Coop
L. Pettit
C. Boon
P. Ramachandra
author_sort H. Coop
title Radical Chemoradiotherapy for Urethral Squamous Cell Carcinoma: Two Case Reports and a Review of the Literature
title_short Radical Chemoradiotherapy for Urethral Squamous Cell Carcinoma: Two Case Reports and a Review of the Literature
title_full Radical Chemoradiotherapy for Urethral Squamous Cell Carcinoma: Two Case Reports and a Review of the Literature
title_fullStr Radical Chemoradiotherapy for Urethral Squamous Cell Carcinoma: Two Case Reports and a Review of the Literature
title_full_unstemmed Radical Chemoradiotherapy for Urethral Squamous Cell Carcinoma: Two Case Reports and a Review of the Literature
title_sort radical chemoradiotherapy for urethral squamous cell carcinoma: two case reports and a review of the literature
publisher Hindawi Limited
series Case Reports in Urology
issn 2090-696X
2090-6978
publishDate 2013-01-01
description Primary urethral squamous cell carcinoma is rare. Its management is particularly challenging owing to the paucity of evidence from randomised trials to inform practice. We report two male and female cases of squamous cell carcinoma of the urethra, which were treated with concomitant cisplatin and radiotherapy. These cases add to the body of case reports that have shown benefit for concomitant chemoradiotherapy in urethral squamous cell carcinoma. They also illustrate that single agent chemotherapy, namely, cisplatin, may be used successfully with limited toxicities.
url http://dx.doi.org/10.1155/2013/194690
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AT lpettit radicalchemoradiotherapyforurethralsquamouscellcarcinomatwocasereportsandareviewoftheliterature
AT cboon radicalchemoradiotherapyforurethralsquamouscellcarcinomatwocasereportsandareviewoftheliterature
AT pramachandra radicalchemoradiotherapyforurethralsquamouscellcarcinomatwocasereportsandareviewoftheliterature
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