High Intestinal and Systemic Levels of Interleukin-23/T-Helper 17 Pathway in Chinese Patients with Inflammatory Bowel Disease

High Intestinal and Systemic Levels of Interleukin-23/T-Helper 17 Pathway in Chinese Patients with Inflammatory Bowel Disease

Interleukin-23/T-helper 17 (IL-23/Th17) pathway plays a key role in the pathogenesis of inflammatory bowel disease (IBD), but little is known about its expression in Chinese population. In this study, we investigated the mRNA and protein levels of IL-12p40, tumor necrosis factor-like cytokine 1A (TL...

Full description

Bibliographic Details
Main Authors:	Lu Song, Rui Zhou, Sha Huang, Feng Zhou, Shufang Xu, Wei Wang, Fengming Yi, Xiaobing Wang, Bing Xia
Format:	Article
Language:	English
Published:	Hindawi Limited 2013-01-01
Series:	Mediators of Inflammation
Online Access:	http://dx.doi.org/10.1155/2013/425915

Similar Items

The Role of Interleukin-23 in Stability of In Vitro T Helper-17 Cells
by: Marjan Taherian, et al.
Published: (2014-04-01)

Targeting the Interleukin-23/Interleukin-17 Inflammatory Pathway: Successes and Failures in the Treatment of Axial Spondyloarthritis
by: Runsheng Wang, et al.
Published: (2021-09-01)

The Role of T Follicular Helper Cells and Interleukin-21 in the Pathogenesis of Inflammatory Bowel Disease
by: Lulu Sun, et al.
Published: (2021-01-01)

Autoimmune Memory T Helper 17 Cell Function and Expansion Are Dependent on Interleukin-23
by: Christopher J. Haines, et al.
Published: (2013-05-01)

Interleukin-35 Is Involved in Angiogenesis/Bone Remodeling Coupling Through T Helper 17/Interleukin-17 Axis
by: Hui Zhang, et al.
Published: (2021-04-01)

Research progress on the role of T helper cells 17 and interleukin 17 in oral mucosal diseases
by: WANG Ziying, et al.
Published: (2021-03-01)

Interleukin-17 and type 17 helper T cells in cancer management and research
by: Llosa NJ, et al.
Published: (2014-03-01)

Expression of T helper 17 cells and interleukin 17 in lupus nephritis patients
by: Nayera Z. Saber, et al.
Published: (2017-07-01)

Pivotal Roles of T-Helper 17-Related Cytokines, IL-17, IL-22, and IL-23, in Inflammatory Diseases
by: Ning Qu, et al.
Published: (2013-01-01)

Inflammatory bowel disease in patients with psoriasis treated with interleukin-17 inhibitors
by: Keira A Fieldhouse, et al.
Published: (2020-04-01)

Distinct roles of interleukin-17 and T helper 17 cells among autoimmune diseases
by: Shintaro Akiyama, et al.
Published: (2021-01-01)

Interleukin-27 Suppresses T Helper-17 Inflammation in Allergic Rhinitis
by: Hong Ouyang, et al.
Published: (2020-12-01)

Endogenous interleukin-10 constrains Th17 cells in patients with inflammatory bowel disease
by: Wilke Cailin M, et al.
Published: (2011-12-01)

Interleukin-15 Constrains Mucosal T Helper 17 Cell Generation: Influence of Mononuclear Phagocytes.
by: Huifeng Yu, et al.
Published: (2015-01-01)

Effector T Helper Cell Subsets in Inflammatory Bowel Diseases
by: Tanbeena Imam, et al.
Published: (2018-06-01)

T follicular helper cells in health and inflammatory bowel disease
by: Thomas, Jessica
Published: (2013)

Differential regulation of interleukin-17 and interferon-y production in inflammatory bowel disease
by: Rovedatti, Laura
Published: (2010)

Interleukin-33 regulates intestinal inflammation by modulating macrophages in inflammatory bowel disease
by: Dong Hyuk Seo, et al.
Published: (2017-04-01)

Association of SIRT-1, T helper 17-associated gene and Antimicrobial Peptides gene in Inflammatory Bowel Disease Patients
by: Magdy Amin El Serafy, et al.
Published: (2017-09-01)

Antagonizing Retinoic Acid-Related-Orphan Receptor Gamma Activity Blocks the T Helper 17/Interleukin-17 Pathway Leading to Attenuated Pro-inflammatory Human Keratinocyte and Skin Responses
by: Florence Ecoeur, et al.
Published: (2019-03-01)

Expression of interleukin-23 and interleukin-17 in the aqueous humor of patients with diabetic retinopathy
by: Hai-Jiang Zhang, et al.
Published: (2020-07-01)

Novel Pharmacological Approaches for Inflammatory Bowel Disease: Targeting Key Intracellular Pathways and the IL-23/IL-17 Axis
by: Leo R. Fitzpatrick
Published: (2012-01-01)

Overexpression of Interleukin-23 and Interleukin-17 in the Lesion of Pemphigus Vulgaris: A Preliminary Study
by: Jixin Xue, et al.
Published: (2014-01-01)

Neonatal T Helper 17 Responses Are Skewed Towards an Immunoregulatory Interleukin-22 Phenotype
by: Hamid R. Razzaghian, et al.
Published: (2021-05-01)

Interferon-β Intensifies Interleukin-23-Driven Pathogenicity of T Helper Cells in Neuroinflammatory Disease
by: Agnieshka Agasing, et al.
Published: (2021-08-01)

Biomarkers of Inflammatory Bowel Disease
by: Yi Fengming, et al.
Published: (2014-01-01)

JNK Pathway-Associated Phosphatase/DUSP22 Suppresses CD4+ T-Cell Activation and Th1/Th17-Cell Differentiation and Negatively Correlates with Clinical Activity in Inflammatory Bowel Disease
by: Rui Zhou, et al.
Published: (2017-07-01)

Fenofibrate Inhibited the Differentiation of T Helper 17 Cells In Vitro
by: Zhou Zhou, et al.
Published: (2012-01-01)

High plasma levels of pro-inflammatory factors interleukin-17 and interleukin-23 are associated with poor outcome of cardiac-arrest patients: a single center experience
by: Yu-Gang Zhuang, et al.
Published: (2020-04-01)

The Interleukin-23/Interleukin-17 Axis Links Adaptive and Innate Immunity in Psoriasis
by: Michael P. Schön, et al.
Published: (2018-06-01)

Polymorphisms in the Toll-Like Receptor and the IL-23/IL-17 Pathways Were Associated with Susceptibility to Inflammatory Bowel Disease in a Danish Cohort.
by: Steffen Bank, et al.
Published: (2015-01-01)

Risk for development of inflammatory bowel disease under inhibition of interleukin 17: A systematic review and meta-analysis.
by: Johan Burisch, et al.
Published: (2020-01-01)

The prevalence and risk factors of cytomegalovirus infection in inflammatory bowel disease in Wuhan, Central China
by: Yi Fengming, et al.
Published: (2013-02-01)

Evaluation of Interleukin17and Interleukin 23 expression in patients with active and latent tuberculosis infection
by: Fatemeh Heidarnezhad, et al.
Published: (2016-08-01)

Intestinal epithelium in inflammatory bowel disease
by: Mehmet eCoskun
Published: (2014-08-01)

Role of intestinal microbiota and metabolites in inflammatory bowel disease
by: Li-Na Dong, et al.
Published: (2019-07-01)

Interleukin-23 and Th17 Cells in the Control of Gut Inflammation
by: Ivan Monteleone, et al.
Published: (2009-01-01)

Lung–infiltrating T helper 17 cells as the major source of interleukin-17A production during pulmonary Cryptococcus neoformans infection
by: Elaheh Movahed, et al.
Published: (2018-11-01)

Regulation of intestine interleukin-17A and interferon-γ productionby interleukin-15
by: Tzu-Hua Huang, et al.
Published: (2014)

Interleukin – 17 and interleukin-10 as inflammatory and prevention biomarkers in periimplant diseases
by: Shirin Zahra Farhad, et al.
Published: (2019-01-01)