mTORC1 Negatively Regulates the Replication of Classical Swine Fever Virus Through Autophagy and IRES-Dependent Translation

mTORC1 Negatively Regulates the Replication of Classical Swine Fever Virus Through Autophagy and IRES-Dependent Translation

Summary: Classical swine fever virus (CSFV) can utilize diverse host signaling pathways for its replication; however, the cross talk between mammalian target of rapamycin (mTOR) and CSFV remains unknown. Here, we describe the potential role of mTOR complex 1 (mTORC1) in promoting CSFV replication vi...

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Bibliographic Details
Main Authors: Qinghua Luo, Li Zhang, Feng Wei, Qiang Fang, Fei Bao, Shijiang Mi, Nan Li, Chengming Wang, Yan Liu, Changchun Tu
Format: Article
Language:English
Published: Elsevier 2018-05-01
Series:iScience
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004218300427

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