Exosomal S100A4 derived from highly metastatic hepatocellular carcinoma cells promotes metastasis by activating STAT3

Exosomal S100A4 derived from highly metastatic hepatocellular carcinoma cells promotes metastasis by activating STAT3

Abstract Intercellular cross-talk plays important roles in cancer progression and metastasis. Yet how these cancer cells interact with each other is still largely unknown. Exosomes released by tumor cells have been proved to be effective cell-to-cell signal mediators. We explored the functional role...

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Bibliographic Details
Main Authors: Haoting Sun, Chaoqun Wang, Beiyuan Hu, Xiaomei Gao, Tiantian Zou, Qin Luo, Mo Chen, Yan Fu, Yuanyuan Sheng, Kaili Zhang, Yan Zheng, Xudong Ren, Shican Yan, Yan Geng, Luyu Yang, Qiongzhu Dong, Lunxiu Qin
Format: Article
Language:English
Published: Nature Publishing Group 2021-05-01
Series:Signal Transduction and Targeted Therapy
Online Access:https://doi.org/10.1038/s41392-021-00579-3

Internet

https://doi.org/10.1038/s41392-021-00579-3

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