bMERB domains are bivalent Rab8 family effectors evolved by gene duplication

bMERB domains are bivalent Rab8 family effectors evolved by gene duplication

In their active GTP-bound form, Rab proteins interact with proteins termed effector molecules. In this study, we have thoroughly characterized a Rab effector domain that is present in proteins of the Mical and EHBP families, both known to act in endosomal trafficking. Within our study, we show that...

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Bibliographic Details
Main Authors: Amrita Rai, Anastasia Oprisko, Jeremy Campos, Yangxue Fu, Timon Friese, Aymelt Itzen, Roger S Goody, Emerich Mihai Gazdag, Matthias P Müller
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2016-08-01
Series:eLife
Subjects:
Rab effectors
Mical
EHBP
Online Access:https://elifesciences.org/articles/18675

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