The effect of sex on immune responses to a homocitrullinated peptide in the DR4-transgenic mouse model of Rheumatoid Arthritis

The effect of sex on immune responses to a homocitrullinated peptide in the DR4-transgenic mouse model of Rheumatoid Arthritis

Rheumatoid Arthritis (RA) is more common and severe in women compared to men. Both women and men with RA express autoantibodies to post-translationally modified antigens, including citrullinated and homocitrullinated proteins or peptides. These autoantibodies are strongly linked with the HLA-DR4 gen...

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Bibliographic Details
Main Authors:	Ewa Cairns, Sheri Saunders, David A. Bell, Garth Blackler, Patrick Lac, Lillian Barra
Format:	Article
Language:	English
Published:	Elsevier 2020-01-01
Series:	Journal of Translational Autoimmunity
Subjects:	Rheumatoid arthritis Anti-citrullinated protein/peptide antibodies Anti-homocitrullinated (carbamylated) protein/peptide antibodies Sex Mouse model Shared epitope
Online Access:	http://www.sciencedirect.com/science/article/pii/S2589909020300204

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