TGF-β downregulation-induced cancer cell death is finely regulated by the SAPK signaling cascade

TGF-β downregulation-induced cancer cell death is finely regulated by the SAPK signaling cascade

Cancer: Tipping the signaling balance Reducing the levels of the multifunctional protein transforming growth factor (TGF)-β in cancer cells prevents tumor growth in mice. Previous studies have shown that high levels of TGF-β in cancerous tissue are associated with accelerated disease progression. Hy...

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Bibliographic Details
Main Authors: Zhezhu Han, Dongxu Kang, Yeonsoo Joo, Jihyun Lee, Geun-Hyeok Oh, Soojin Choi, Suwan Ko, Suyeon Je, Hye Jin Choi, Jae J. Song
Format: Article
Language:English
Published: Nature Publishing Group 2018-12-01
Series:Experimental and Molecular Medicine
Online Access:https://doi.org/10.1038/s12276-018-0189-8

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https://doi.org/10.1038/s12276-018-0189-8

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