The Outcome of Critically Ill COVID-19 Patients Is Linked to Thromboinflammation Dominated by the Kallikrein/Kinin System

The Outcome of Critically Ill COVID-19 Patients Is Linked to Thromboinflammation Dominated by the Kallikrein/Kinin System

An important manifestation of severe COVID-19 is the ARDS-like lung injury that is associated with vascular endothelialitis, thrombosis, and angiogenesis. The intravascular innate immune system (IIIS), including the complement, contact, coagulation, and fibrinolysis systems, which is crucial for rec...

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Bibliographic Details
Main Authors: Miklós Lipcsey, Barbro Persson, Oskar Eriksson, Anna M. Blom, Karin Fromell, Michael Hultström, Markus Huber-Lang, Kristina N. Ekdahl, Robert Frithiof, Bo Nilsson
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Immunology
Subjects:
thromboinflammation
kallikrein/kinin system
complement system
coagulation system
fibrinolysis system
COVID-19
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.627579/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2021.627579/full

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