The role of FNAC in diagnostically challenging malignant lesions of breast

Background: Fine needle aspiration cytology is a simple investigation to evaluate the malignant tumors of the breast when compared to tru-cut biopsy. It is invaluable in the diagnosis of the common invasive carcinoma of the breast including its subtypes. The morphology of the uncommon subtypes and o...

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Main Authors: Rajyalakshmi Rallapalli, Lakshmi V Chavali, Bhaskar V Rani, Ramana V Kada, Beulah P Maddirala
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2019-01-01
Series:Journal of Dr. NTR University of Health Sciences
Subjects:
Online Access:http://www.jdrntruhs.org/article.asp?issn=2277-8632;year=2019;volume=8;issue=4;spage=250;epage=256;aulast=Rallapalli
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spelling doaj-88e2a038e9b9460986597f37f5d38d042020-11-25T02:48:56ZengWolters Kluwer Medknow PublicationsJournal of Dr. NTR University of Health Sciences2277-86322019-01-018425025610.4103/JDRNTRUHS.JDRNTRUHS_83_19The role of FNAC in diagnostically challenging malignant lesions of breastRajyalakshmi RallapalliLakshmi V ChavaliBhaskar V RaniRamana V KadaBeulah P MaddiralaBackground: Fine needle aspiration cytology is a simple investigation to evaluate the malignant tumors of the breast when compared to tru-cut biopsy. It is invaluable in the diagnosis of the common invasive carcinoma of the breast including its subtypes. The morphology of the uncommon subtypes and other rare tumors are the source of diagnostic confusion. Aims: The objective of this study is to assess the role of FNAC in diagnostically challenging malignant lesions of the breast. Methods and Material: The study included 526 female patients with palpable breast lumps subjected to FNAC for one year from November 2015 to October 2016 in the department of pathology. The cytology features of these patients were studied and correlated with histopathology. Results: Diagnostic difficulty was encountered in certain tumors having either bland cytology or a predominant discrete pattern or a combination of extracellular mucin and papillary pattern. These were reanalyzed in correlation with histopathology, clinical findings, radiology and immunohistochemistry. Conclusions: Awareness of the morphology of these rare lesions improves the diagnostic accuracy making cytology a more efficient tool for the preoperative assessment of malignant breast tumors.http://www.jdrntruhs.org/article.asp?issn=2277-8632;year=2019;volume=8;issue=4;spage=250;epage=256;aulast=Rallapallibreastcribriformfine needle aspiration cytologymicropapillaeplasmacytoma
collection DOAJ
language English
format Article
sources DOAJ
author Rajyalakshmi Rallapalli
Lakshmi V Chavali
Bhaskar V Rani
Ramana V Kada
Beulah P Maddirala
spellingShingle Rajyalakshmi Rallapalli
Lakshmi V Chavali
Bhaskar V Rani
Ramana V Kada
Beulah P Maddirala
The role of FNAC in diagnostically challenging malignant lesions of breast
Journal of Dr. NTR University of Health Sciences
breast
cribriform
fine needle aspiration cytology
micropapillae
plasmacytoma
author_facet Rajyalakshmi Rallapalli
Lakshmi V Chavali
Bhaskar V Rani
Ramana V Kada
Beulah P Maddirala
author_sort Rajyalakshmi Rallapalli
title The role of FNAC in diagnostically challenging malignant lesions of breast
title_short The role of FNAC in diagnostically challenging malignant lesions of breast
title_full The role of FNAC in diagnostically challenging malignant lesions of breast
title_fullStr The role of FNAC in diagnostically challenging malignant lesions of breast
title_full_unstemmed The role of FNAC in diagnostically challenging malignant lesions of breast
title_sort role of fnac in diagnostically challenging malignant lesions of breast
publisher Wolters Kluwer Medknow Publications
series Journal of Dr. NTR University of Health Sciences
issn 2277-8632
publishDate 2019-01-01
description Background: Fine needle aspiration cytology is a simple investigation to evaluate the malignant tumors of the breast when compared to tru-cut biopsy. It is invaluable in the diagnosis of the common invasive carcinoma of the breast including its subtypes. The morphology of the uncommon subtypes and other rare tumors are the source of diagnostic confusion. Aims: The objective of this study is to assess the role of FNAC in diagnostically challenging malignant lesions of the breast. Methods and Material: The study included 526 female patients with palpable breast lumps subjected to FNAC for one year from November 2015 to October 2016 in the department of pathology. The cytology features of these patients were studied and correlated with histopathology. Results: Diagnostic difficulty was encountered in certain tumors having either bland cytology or a predominant discrete pattern or a combination of extracellular mucin and papillary pattern. These were reanalyzed in correlation with histopathology, clinical findings, radiology and immunohistochemistry. Conclusions: Awareness of the morphology of these rare lesions improves the diagnostic accuracy making cytology a more efficient tool for the preoperative assessment of malignant breast tumors.
topic breast
cribriform
fine needle aspiration cytology
micropapillae
plasmacytoma
url http://www.jdrntruhs.org/article.asp?issn=2277-8632;year=2019;volume=8;issue=4;spage=250;epage=256;aulast=Rallapalli
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