Reduced order modeling and analysis of the human complement system.

Complement is an important pathway in innate immunity, inflammation, and many disease processes. However, despite its importance, there are few validated mathematical models of complement activation. In this study, we developed an ensemble of experimentally validated reduced order complement models....

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Bibliographic Details
Main Authors: Adithya Sagar, Wei Dai, Mason Minot, Rachel LeCover, Jeffrey D Varner
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5695804?pdf=render