Generation of functional NaV1.5 current by endogenous transcriptional activation of SCN5A

The sodium channel NaV1.5, which is encoded by the SCN5A gene, underlies the fast upstroke of cardiac action potential and thus plays a crucial role in cardiac electrophysiology, but the mechanism governing the regulation of NaV1.5 has not been fully elucidated. The newly developed clustered regular...

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Bibliographic Details
Main Authors: Liang Xu, Rui Shi
Format: Article
Language:English
Published: Taylor & Francis Group 2021-01-01
Series:Biotechnology & Biotechnological Equipment
Subjects:
Online Access:http://dx.doi.org/10.1080/13102818.2021.1892524