The Behavioral Consequence of Phenylketonuria in Mice Depends on the Genetic Background

The Behavioral Consequence of Phenylketonuria in Mice Depends on the Genetic Background

To unravel the role of gene mutations in the healthy and the diseased state, countless studies have tried to link genotype with phenotype. However, over the years, it became clear that the strain of mice can influence these results. Nevertheless, identical gene mutations in different strains are oft...

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Bibliographic Details
Main Authors: Vibeke Marijn Bruinenberg, Els van der Goot, Danique van Vliet, Martijn J. de Groot, Priscila N. Mazzola, Rebecca Heiner-Fokkema, Martijn van Faassen, Francjan J. van Spronsen, Eddy A Van Der Zee
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-12-01
Series:Frontiers in Behavioral Neuroscience
Subjects:
spatial memory
phenotype
learning and memory
Genotype
mouse models
phenylketonuria
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnbeh.2016.00233/full

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