The relationships between transforming growth factors <i>β</i> and free thyroxine and progesterone in the ovarian cysts, preovulatory follicles, and the serum of sows

• Main Author: T. Stankiewicz
• Format: Article
• Language: English
• Published: Copernicus Publications 2017-06-01
• Series: Archives Animal Breeding
• Online Access: http://www.arch-anim-breed.net/60/131/2017/aab-60-131-2017.pdf
• ISSN: 0003-9438; 2363-9822

The aim of the study was to determine the relationships between bone morphogenetic protein 15 (BMP-15) and growth differentiation factor 9 (GDF-9) concentrations and free thyroxine (FT₄) and progesterone (P₄) concentrations in follicular cysts, preovulatory follicles, and the serum of sows (cyst-bearing (<i>n</i> = 26) and non-cyst-bearing (<i>n</i> =  26)). FT₄ and P₄ concentrations were higher in the cystic fluid than in the fluid of preovulatory follicles (<i>p</i> &lt;  0.01 and <i>p</i> &lt;  0.05 respectively). BMP-15 and GDF-9 concentrations were higher in the serum of cyst-bearing sows than non-cyst-bearing sows (<i>p</i> &lt;  0.05) and higher in the cystic fluid than in the follicular fluid (<i>p</i> &lt;  0.05). In the cysts and preovulatory follicles, GDF-9 concentration was higher than in serum (<i>p</i> &lt;  0.01). FT₄ concentration in the serum of cystic sows was correlated with BMP-15 (<i>r</i> =  0.50, <i>p</i> &lt;  0.05) and GDF-9 (<i>r</i> =  0.62, <i>p</i> &lt;  0.01) concentrations in serum. In the serum of non-cyst-bearing sows, a positive correlation between P₄ concentration and BMP-15 concentration (<i>r</i> =  0.60, <i>p</i> &lt;  0.01) was detected. <br><br> These data will help provide insight into the role of BMP-15, GDF-9, FT₄, and P₄ during cyst formation in sows.