| Summary: | <span style="font-family: Times New Roman; font-size: small;"> </span><p style="margin: 0cm 0cm 0pt; text-align: justify; text-indent: 35.4pt; mso-layout-grid-align: none;" class="MsoNormal"><span lang="EN-US" style="font-size: 8pt; mso-ansi-language: EN-US;"><span style="font-family: Times New Roman;">Gold <span style="color: #231f20;">nanoparticles (AuNPs) </span>have attracted increasing interest in diagnosis and therapy of disease, being widely used in biosensors, cancer cell imaging, photothermal therapy, drug delivery and as antimicrobial agents. Using <span style="color: black;">a </span><span style="mso-bidi-font-weight: bold;">well diffusion method and an evaluation of bacterial growth in liquid media we assessed the antimicrobial properties of chitosan capped </span><span style="color: black;">AuNPs with different sizes and concentrations. The obtained data showed that chitosan capped Au NPs and chitosan inhibited the growth of <em>Escherichia coli</em> and <em>Staphylococcus aureus</em>. The inhibition effect was due more likely to the antimicrobial properties of chitosan <a name="OLE_LINK2"></a><a name="OLE_LINK1"><span style="mso-bookmark: OLE_LINK2;">rather to the </span></a>AuNPs. Our results suggest that Au NPs can inhibit the antimicrobial activity of chitosan, regardless of sizes and concentrations used, in the case of both tested bacteria. </span><strong></strong></span></span></p><span style="font-family: Times New Roman; font-size: small;"> </span>
|
|---|
