ICT1 Promotes Osteosarcoma Cell Proliferation and Inhibits Apoptosis via STAT3/BCL-2 Pathway

ICT1 Promotes Osteosarcoma Cell Proliferation and Inhibits Apoptosis via STAT3/BCL-2 Pathway

Osteosarcoma (OS) is a familiar malignant bone tumor that occurs mainly in adolescents. Immature colon carcinoma transcript-1 (ICT1) is an important member of the large mitoribosomal subunit in mitochondrial ribosomes, which has been shown to be closely related to tumorigenesis. Its expression and f...

Full description

Bibliographic Details
Main Authors:	Xiaohui Pan, Jingxue Tan, Xiaokun Weng, Rui Du, Yuqing Jiang, Yiping Weng, Dong Zhou, Yifei Shen
Format:	Article
Language:	English
Published:	Hindawi Limited 2021-01-01
Series:	BioMed Research International
Online Access:	http://dx.doi.org/10.1155/2021/8971728

Similar Items

Serine/Threonine Kinase 35, a Target Gene of STAT3, Regulates the Proliferation and Apoptosis of Osteosarcoma Cells
by: Zhong Wu, et al.
Published: (2018-01-01)

miR-1297 Suppresses Osteosarcoma Proliferation and Aerobic Glycolysis by Regulating PFKFB2
by: Pan X, et al.
Published: (2020-11-01)

Silencing of Eag1 Gene Inhibits Osteosarcoma Proliferation and Migration by Targeting STAT3-VEGF Pathway
by: Xinyu Wu, et al.
Published: (2015-01-01)

Expression of Bcl-2 in canine osteosarcoma
by: F. Piro, et al.
Published: (2015-03-01)

FBXO2 modulates STAT3 signaling to regulate proliferation and tumorigenicity of osteosarcoma cells
by: Xunming Zhao, et al.
Published: (2020-06-01)

Bufalin Inhibits Proliferation and Induces Apoptosis in Osteosarcoma Cells by Downregulating MicroRNA-221
by: Jianjun Zhang, et al.
Published: (2016-01-01)

Silencing of Kv1.5 Gene Inhibits Proliferation and Induces Apoptosis of Osteosarcoma Cells
by: Jin Wu, et al.
Published: (2015-11-01)

MiR-133b is down-regulated in human osteosarcoma and inhibits osteosarcoma cells proliferation, migration and invasion, and promotes apoptosis.
by: Huafu Zhao, et al.
Published: (2013-01-01)

The effects of MEX3A knockdown on proliferation, apoptosis and migration of osteosarcoma cells
by: Bangmin Wang, et al.
Published: (2021-04-01)

Expression of miR-664-3p in Osteosarcoma and Its Effects on the Proliferation and Apoptosis of Osteosarcoma Cells
by: Ye LI, et al.
Published: (2019-10-01)

miR-31 inhibits proliferation and promotes apoptosis of osteosarcoma cells through PAX9
by: Le-Meng Chao, et al.
Published: (2020-07-01)

Icarisid II inhibits the proliferation of human osteosarcoma cells by inducing apoptosis and cell cycle arrest
by: Yuanyuan Tang, et al.
Published: (2017-05-01)

Polysaccharides from Dendrobium officinale inhibit proliferation of osteosarcoma cells and enhance cisplatin-induced apoptosis
by: Xiaofeng Zhang, et al.
Published: (2020-10-01)

Ginsenoside Rg3 Suppresses Proliferation and Induces Apoptosis in Human Osteosarcoma
by: Yi Li, et al.
Published: (2018-01-01)

Lestaurtinib inhibition of the Jak/STAT signaling pathway in hodgkin lymphoma inhibits proliferation and induces apoptosis.
by: Tania Diaz, et al.
Published: (2011-01-01)

Oleanane triterpenoid CDDO-Me induces apoptosis in multidrug resistant osteosarcoma cells through inhibition of Stat3 pathway
by: Choy Edwin, et al.
Published: (2010-05-01)

Characterization of STAT3 Activation in Osteosarcoma
by: Fossey, Stacey L.
Published: (2010)

HOXA10 induces BCL2 expression, inhibits apoptosis, and promotes cell proliferation in gastric cancer
by: Chenlong Song, et al.
Published: (2019-09-01)

Postconditioning inhibits myocardial apoptosis during prolonged reperfusion via a JAK2-STAT3-Bcl-2 pathway
by: Liang Degang, et al.
Published: (2011-08-01)

The role of the Bcl-2 family in proliferation and apoptosis and in mediating the development of lymphatic diseases
by: Eipper-Mains, Marcie A., 1979-
Published: (2005)

Lentivirus-induced knockdown of IARS2 expression inhibits the proliferation and promotes the apoptosis of human osteosarcoma cells
by: Lin, F., et al.
Published: (2022)

Effects of Inonotus obliquus Polysaccharides on Proliferation, Invasion, Migration, and Apoptosis of Osteosarcoma Cells
by: Baohui Su, et al.
Published: (2020-01-01)

Reduced cell proliferation and promotion of apoptosis by Leu5AMD in osteosarcoma cells
by: Wu Xiaofeng, et al.
Published: (2017-01-01)

Aberrant Expression of PAFAH1B3 Affects Proliferation and Apoptosis in Osteosarcoma
by: Jian Fan, et al.
Published: (2021-05-01)

Stat3 Expression and Its Correlation with Proliferation and Apoptosis/Autophagy in Gliomas
by: Valentina Caldera, et al.
Published: (2008-01-01)

HOTAIR Promotes Cisplatin Resistance of Osteosarcoma Cells by Regulating Cell Proliferation, Invasion, and Apoptosis via miR-106a-5p/STAT3 Axis
by: Jiankuo Guo, et al.
Published: (2020-08-01)

MiR-4328 inhibits proliferation, metastasis and induces apoptosis in keloid fibroblasts by targeting BCL2 expression
by: Tang Hongmei, et al.
Published: (2020-09-01)

REG γ knockdown suppresses proliferation by inducing apoptosis and cell cycle arrest in osteosarcoma
by: Zhiqiang Yin, et al.
Published: (2020-04-01)

Thymoquinone decreases F-actin polymerization and the proliferation of human multiple myeloma cells by suppressing STAT3 phosphorylation and Bcl2/Bcl-<sub>XL </sub>expression
by: Badr Gamal, et al.
Published: (2011-12-01)

Resveratrol eliminates cancer stem cells of osteosarcoma by STAT3 pathway inhibition.
by: Lihua Peng, et al.
Published: (2018-01-01)

Inhibition of STAT3 blocks protein synthesis and tumor metastasis in osteosarcoma cells
by: Dongqing Zuo, et al.
Published: (2018-10-01)

Overexpression of TTRAP inhibits cell growth and induces apoptosis in osteosarcoma cells
by: Caihong Zhou, et al.
Published: (2013-02-01)

Testicular Nuclear Receptor 4 Regulates Proliferation and Apoptosis of Bladder Cancer via Bcl-2
by: Huan Wang, et al.
Published: (2021-09-01)

Phosphorylated Forms of STAT1, STAT3 and STAT5 Are Expressed in Proliferating but Not Involuted Infantile Hemangioma
by: Lucy Sulzberger, et al.
Published: (2018-04-01)

LncRNA SNHG16 promotes proliferation, migration and invasion of osteosarcoma cells by targeting miR-1301/BCL9 axis
by: Xueli Wang, et al.
Published: (2019-06-01)

TRIM52 promotes colorectal cancer cell proliferation through the STAT3 signaling
by: Shengli Pan, et al.
Published: (2019-03-01)

Effect of abnormal MZF1 and FoxM1 expression on cell proliferation and apoptosis in osteosarcoma
by: Lin Liu, et al.
Published: (2018-04-01)

KIF21B Expression in Osteosarcoma and Its Regulatory Effect on Osteosarcoma Cell Proliferation and Apoptosis Through the PI3K/AKT Pathway
by: Songjia Ni, et al.
Published: (2021-01-01)

Effects of MicroRNA-206 on Osteosarcoma Cell Proliferation, Apoptosis, Migration and Invasion by Targeting ANXA2 Through the AKT Signaling Pathway
by: Bao-Long Pan, et al.
Published: (2018-02-01)

Costunolide inhibits osteosarcoma growth and metastasis via suppressing STAT3 signal pathway
by: Xinmeng Jin, et al.
Published: (2020-01-01)