Adipose sirtuin 6 drives macrophage polarization toward M2 through IL-4 production and maintains systemic insulin sensitivity in mice and humans

Adipose sirtuin 6 drives macrophage polarization toward M2 through IL-4 production and maintains systemic insulin sensitivity in mice and humans

Obesity and diabetes: A control protein in fat A protein in adipose tissue (composed of fat cells) helps protect against inflammation and the development of resistance to insulin that develops in obesity and can lead to type 2 diabetes. Researchers in South Korea, led by Eun Ju Bae at Woosuk Univers...

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Bibliographic Details
Main Authors:	Mi-Young Song, Sang Hoon Kim, Ga-Hee Ryoo, Mi-Kyung Kim, Hye-Na Cha, So-Young Park, Hong Pil Hwang, Hee Chul Yu, Eun Ju Bae, Byung-Hyun Park
Format:	Article
Language:	English
Published:	Nature Publishing Group 2019-05-01
Series:	Experimental and Molecular Medicine
Online Access:	https://doi.org/10.1038/s12276-019-0256-9

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