A three-component synthesis of functionalized ketenimines by the reaction of alkyl isocyanides and dialkyl acetylenedicarboxylates in the presence of 2-quinolinol

• Main Authors: BITA MOHTAT, HOORIEH DJAHANIANI, ISSA YAVARI, KOBRA NADERI
• Format: Article
• Language: English
• Published: Serbian Chemical Society 2011-01-01
• Series: Journal of the Serbian Chemical Society
• Subjects: ketenimines; 1-azadienes; alkyl isocyanides; acetylenic esters; NH-acids; multi-component reaction
• Online Access: http://www.shd.org.rs/JSCS/Vol76/No1/02_4697_4094.pdf
• ISSN: 0352-5139

The 1:1 reactive intermediates generated by the addition of alkyl isocyanides to dialkyl acetylenedicarboxylates were trapped by 2-quinolinol to yield highly functionalized ketenimines and, in some cases, minor amounts of 1-azabuta-1,3-dienes.