Structure - Activity Relationship of Mutant KatG from INH resistant Mycobacterium tuberculosis

Mutation in katG gene of Mycobacterium tuberculosis encoding catalase-peroxidase that damage its enzyme activities is well associated with isoniazid (INH) resistance. The katG gene from INH resistant strain of M. tuberculosis clinical isolate L19 has been observed in previous study, carrying mutati...

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Bibliographic Details
Main Authors: Purkan Purkan, Sri Puji Astuti Wahyuningsih, Wiwin Retnowati, Diah Amelia, Alfain Noerdin Alimny
Format: Article
Language:English
Published: Journal of Pure and Applied Microbiology 2017-06-01
Series:Journal of Pure and Applied Microbiology
Subjects:
Online Access:https://microbiologyjournal.org/structure-activity-relationship-of-mutant-katg-frominh-resistant-mycobacterium-tuberculosis/