Comparative Proteome-Wide Analysis of Bone Marrow Microenvironment of β-Thalassemia/Hemoglobin E

Comparative Proteome-Wide Analysis of Bone Marrow Microenvironment of β-Thalassemia/Hemoglobin E

β-thalassemia/Hb E is a global health issue, which is characterized by a range of clinical symptoms from a mild and asymptomatic anemia to severe disorders that require transfusions from infancy. Pathological mechanisms of the disease involve the excess of unmatched alpha globin and iron ov...

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Bibliographic Details
Main Authors: Saranyoo Ponnikorn, Rungrawee Mongkolrob, Suwit Klongthalay, Sittiruk Roytrakul, Kitima Srisanga, Sumalee Tungpradabkul, Suradej Hongeng
Format: Article
Language:English
Published: MDPI AG 2019-02-01
Series:Proteomes
Subjects:
β-thalassemia/Hb E
bone marrow
ineffective erythropoiesis
proteomics
oxidative stress
Apolipoprotein D
Online Access:https://www.mdpi.com/2227-7382/7/1/8

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