Colon cryptogenesis: asymmetric budding.

The process of crypt formation and the roles of Wnt and cell-cell adhesion signaling in cryptogenesis are not well described; but are important to the understanding of both normal and cancer colon crypt biology. A quantitative 3D-microscopy and image analysis technique is used to study the frequency...

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Bibliographic Details
Main Authors: Chin Wee Tan, Yumiko Hirokawa, Bruce S Gardiner, David W Smith, Antony W Burgess
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3804607?pdf=render

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