Acute Putrescine Supplementation with Schwann Cell Implantation Improves Sensory and Serotonergic Axon Growth and Functional Recovery in Spinal Cord Injured Rats
Schwann cell (SC) transplantation exhibits significant potential for spinal cord injury (SCI) repair and its use as a therapeutic modality has now progressed to clinical trials for subacute and chronic human SCI. Although SC implants provide a receptive environment for axonal regrowth and support fu...
Main Authors: | J. Bryan Iorgulescu, Samik P. Patel, Jack Louro, Christian M. Andrade, Andre R. Sanchez, Damien D. Pearse |
---|---|
Format: | Article |
Language: | English |
Published: |
Hindawi Limited
2015-01-01
|
Series: | Neural Plasticity |
Online Access: | http://dx.doi.org/10.1155/2015/186385 |
Similar Items
-
Permissive Schwann Cell Graft/Spinal Cord Interfaces for Axon Regeneration
by: Ryan R. Williams, et al.
Published: (2015-01-01) -
The Role of the Serotonergic System in Locomotor Recovery after Spinal Cord Injury
by: Mousumi eGhosh, et al.
Published: (2015-02-01) -
Combining Neurotrophin-Transduced Schwann Cells and Rolipram to Promote Functional Recovery from Subacute Spinal Cord Injury
by: Govinder Flora, et al.
Published: (2013-12-01) -
Respiratory axon regeneration in the chronically injured spinal cord
by: Lan Cheng, et al.
Published: (2021-07-01) -
The developmental emergence of differential brainstem serotonergic control of the sensory spinal cord
by: F. Schwaller, et al.
Published: (2017-05-01)