Pursuing Experimental Reproducibility: An Efficient Protocol for the Preparation of Cerebrospinal Fluid Samples for NMR-Based Metabolomics and Analysis of Sample Degradation

Pursuing Experimental Reproducibility: An Efficient Protocol for the Preparation of Cerebrospinal Fluid Samples for NMR-Based Metabolomics and Analysis of Sample Degradation

NMR-based metabolomics investigations of human biofluids offer great potential to uncover new biomarkers. In contrast to protocols for sample collection and biobanking, procedures for sample preparation prior to NMR measurements are still heterogeneous, thus compromising the comparability of the res...

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Bibliographic Details
Main Authors: Benjamin Albrecht, Elena Voronina, Carola Schipke, Oliver Peters, Maria Kristina Parr, M. Dolores Díaz-Hernández, Nils E. Schlörer
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:Metabolites
Subjects:
cerebrospinal fluid
CSF
NMR metabolomics
sample preparation
pH
sample degradation
Online Access:https://www.mdpi.com/2218-1989/10/6/251

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