Multivariate optimisation and validation of the analytical GC-FID for evaluating organic solvents in radiopharmaceutical

Multivariate optimisation and validation of the analytical GC-FID for evaluating organic solvents in radiopharmaceutical

Objective: Analytical gas chromatography in line with a flame ionisation detector (GC-FID) method was developed and validated for evaluating organic solvents in radiopharmaceutical samples [18F]fluoro-ethyl-tyrosine ([18F]FET), [18F]fluoromisonidazole ([18F]FMISO) and [18F]fluorothymidine ([18F]FLT)...

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Bibliographic Details
Main Authors: Hishar Hassan, Muhamad Faiz Othman, Zainul Amiruddin Zakaria, Fathinul Fikri Ahmad Saad, Hairil Rashmizal Abdul Razak
Format: Article
Language:English
Published: Elsevier 2021-09-01
Series:Journal of King Saud University: Science
Subjects:
Organic solvent analysis
Quality control analysis
Gas chromatography-FID
Carrier gas flow
Injection split ratio
Radiopharmaceutical
Online Access:http://www.sciencedirect.com/science/article/pii/S1018364721002159

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http://www.sciencedirect.com/science/article/pii/S1018364721002159

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