Computer simulations explain the anomalous temperature optimum in a cold-adapted enzyme

Enzymes from organisms inhabiting cold environments (psychrophiles) have adapted to catalyzing chemical reactions at near freezing temperatures. Here – using molecular dynamics simulations – the authors analyze cold adaptation of psychrophilic α-amylase and provide the structural basis for its low a...

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Bibliographic Details
Main Authors: Jaka Sočan, Miha Purg, Johan Åqvist
Format: Article
Language:English
Published: Nature Publishing Group 2020-05-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-16341-2

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