Co-receptor and co-stimulation blockade for mixed chimerism and tolerance without myelosuppressive conditioning

Co-receptor and co-stimulation blockade for mixed chimerism and tolerance without myelosuppressive conditioning

<p>Abstract</p> <p>Background</p> <p>A major challenge in the application of marrow transplantation as a route to immunological tolerance of a transplanted organ is to achieve hematopoietic stem cell (HSC) engraftment with minimal myelosuppressive treatments.</p>...

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Bibliographic Details
Main Authors: Fairchild Paul J, Daley Stephen, Graca Luis, Cobbold Stephen P, Waldmann Herman
Format: Article
Language:English
Published: BMC 2006-04-01
Series:BMC Immunology
Online Access:http://www.biomedcentral.com/1471-2172/7/9

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