Full-Term Human Placental Macrophages Eliminate Coxiella burnetii Through an IFN-γ Autocrine Loop

Full-Term Human Placental Macrophages Eliminate Coxiella burnetii Through an IFN-γ Autocrine Loop

The intracellular bacterium Coxiella burnetii is responsible for Q fever, an infectious disease that increases the risk of abortion, preterm labor, and stillbirth in pregnant women. It has been shown that C. burnetii replicates in BeWo trophoblast cell line and inhibits the activation and maturation...

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Bibliographic Details
Main Authors: Soraya Mezouar, Imene Benammar, Asma Boumaza, Aïssatou Bailo Diallo, Céline Chartier, Christophe Buffat, John Boudjarane, Philippe Halfon, Maria Katsogiannou, Jean-Louis Mege
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-10-01
Series:Frontiers in Microbiology
Subjects:
Coxiella burnetii
inflammation
interferon-γ
macrophages
multinuclear giant cells
placenta
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2019.02434/full

Internet

https://www.frontiersin.org/article/10.3389/fmicb.2019.02434/full

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