Epithelial-derived IL-33 promotes intestinal tumorigenesis in Apc Min/+ mice

Epithelial-derived IL-33 promotes intestinal tumorigenesis in Apc Min/+ mice

Abstract Increased expression of Interleukin (IL)-33 has been detected in intestinal samples of patients with ulcerative colitis, a condition associated with increased risk for colon cancer, but its role in the development of colorectal cancer has yet to be fully examined. Here, we investigated the...

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Main Authors: Zhengxiang He, Lili Chen, Fabricio O. Souto, Claudia Canasto-Chibuque, Gerold Bongers, Madhura Deshpande, Noam Harpaz, Huaibin M. Ko, Kevin Kelley, Glaucia C. Furtado, Sergio A. Lira
Format: Article
Language:English
Published: Nature Publishing Group 2017-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-05716-z

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