p53-Dependent and -Independent Epithelial Integrity: Beyond miRNAs and Metabolic Fluctuations

In addition to its classical roles as a tumor suppressor, p53 has also been shown to act as a guardian of epithelial integrity by inducing the microRNAs that target transcriptional factors driving epithelial–mesenchymal transition. On the other hand, the ENCODE project demonstrated an enri...

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Bibliographic Details
Main Authors: Tsukasa Oikawa, Yutaro Otsuka, Hisataka Sabe
Format: Article
Language:English
Published: MDPI AG 2018-05-01
Series:Cancers
Subjects:
p53
EMT
Online Access:http://www.mdpi.com/2072-6694/10/6/162