Crosstalk and the evolvability of intracellular communication

The evolutionary rationale behind the extensive crosstalk between Metazoan signalling pathways remains elusive. Here the authors provide evidence that crosstalk in the human signalling network evolves as a means to allow efficient diversification of cellular responses to the same signals between dif...

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Bibliographic Details
Main Authors: Michael A. Rowland, Joseph M. Greenbaum, Eric J. Deeds
Format: Article
Language:English
Published: Nature Publishing Group 2017-07-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/ncomms16009