Dexamethasone Preconditioning in Cardiac Procedures Reduces Decreased Antithrombin Activity and Is Associated to Beneficial Outcomes: Role of Endothelium

Dexamethasone Preconditioning in Cardiac Procedures Reduces Decreased Antithrombin Activity and Is Associated to Beneficial Outcomes: Role of Endothelium

Introduction: Decreased antithrombin (AT) activity in patients scheduled for cardiovascular surgery under cardiopulmonary bypass (CPB) is related to increased postoperative complications and hospitalization time. Indirect evidence suggests that glucocorticoids mitigate this decreased AT activity. To...

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Bibliographic Details
Main Authors: Vicente Muedra, Lucrecia Moreno, Vicente Rodilla, Cristina Arce, Fermi Montó, Águeda Blázquez, Paloma Pérez, Pilar D’Ocón
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-09-01
Series:Frontiers in Pharmacology
Subjects:
angiogenesis
antithrombin
cardiac surgery
cardiopulmonary bypass
dexamethasone
endothelial function
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2018.01014/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2018.01014/full

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