PIK3CA mutation is associated with increased local failure in lung stereotactic body radiation therapy (SBRT)

PIK3CA mutation is associated with increased local failure in lung stereotactic body radiation therapy (SBRT)

Objectives: Hyperactivation of the phosphatidylinositol-3-kinase (PI3K) pathway has been associated with radioresistance. It is unclear whether such mutations confer suboptimal local control for patients who receive lung stereotactic body radiation therapy (SBRT). Our objective was to examine whethe...

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Bibliographic Details
Main Authors: Natalie A. Lockney, T. Jonathan Yang, David Barron, Emily Gelb, Daphna Y. Gelblum, Ellen Yorke, Weiji Shi, Zhigang Zhang, Andreas Rimner, Abraham J. Wu
Format: Article
Language:English
Published: Elsevier 2017-12-01
Series:Clinical and Translational Radiation Oncology
Online Access:http://www.sciencedirect.com/science/article/pii/S2405630817300812

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