Interactions of TLR4 and PPARγ, Dependent on AMPK Signalling Pathway Contribute to Anti-Inflammatory Effects of Vaccariae Hypaphorine in Endothelial Cells

Interactions of TLR4 and PPARγ, Dependent on AMPK Signalling Pathway Contribute to Anti-Inflammatory Effects of Vaccariae Hypaphorine in Endothelial Cells

Background /Aims: Accumulating evidence indicates that endothelial inflammation is one of the critical determinants in pathogenesis of atherosclerotic cardiovascular disease. Our previous studies had demonstrated that Vaccariae prevented high glucose or oxidative stress-triggered endothelial dysfunc...

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Bibliographic Details
Main Authors: Haijian Sun, Xuexue Zhu, Wei Lin, Yuetao Zhou, Weiwei Cai, Liying Qiu
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2017-07-01
Series:Cellular Physiology and Biochemistry
Subjects:
Endothelial inflammation
LPS
PPARγ
TLR4
AMPK
Online Access:http://www.karger.com/Article/FullText/478920

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