Investigation of Anti-Tumor Effects of an MLK1 Inhibitor in Prostate and Pancreatic Cancers

It was shown that mixed lineage kinase 1 (MLK1) regulates pancreatic cancer growth; however, its role in prostate cancer remains unclear. We showed that MLK1 is a tumor marker in prostate cancer by analyzing clinical gene expression data and identified a novel MLK1 inhibitor (NSC14465) from the comp...

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Bibliographic Details
Main Authors: Yu-Ching Fan, Kai-Chen Hsu, Tony-Eight Lin, Dietmar Zechner, Sung-Po Hsu, Yuan-Chin Tsai
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Biology
Subjects:
Online Access:https://www.mdpi.com/2079-7737/10/8/742