Testosterone Attenuates Group 2 Innate Lymphoid Cell-Mediated Airway Inflammation

Testosterone Attenuates Group 2 Innate Lymphoid Cell-Mediated Airway Inflammation

Sex hormones regulate many autoimmune and inflammatory diseases, including asthma. As adults, asthma prevalence is 2-fold greater in women compared to men. The number of group 2 innate lymphoid cells (ILC2) is increased in patients with asthma, and we investigate how testosterone attenuates ILC2 fun...

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Bibliographic Details
Main Authors: Jacqueline-Yvonne Cephus, Matthew T. Stier, Hubaida Fuseini, Jeffrey A. Yung, Shinji Toki, Melissa H. Bloodworth, Weisong Zhou, Kasia Goleniewska, Jian Zhang, Sarah L. Garon, Robert G. Hamilton, Vasiliy V. Poloshukin, Kelli L. Boyd, R. Stokes Peebles, Jr., Dawn C. Newcomb
Format: Article
Language:English
Published: Elsevier 2017-11-01
Series:Cell Reports
Subjects:
innate lymphoid cells
testosterone
sex hormones
asthma
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124717315905

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