Human Papillomaviruses Target the DNA Damage Repair and Innate Immune Response Pathways to Allow for Persistent Infection

Persistent infection with high-risk human papillomaviruses (HPVs) is the major risk factor associated with development of anogenital and oropharyngeal cancers. Initial infection by HPVs occurs into basal epithelial cells where viral genomes are established as nuclear episomes and persist until clear...

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Bibliographic Details
Main Authors: Elona Gusho, Laimonis Laimins
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Viruses
Subjects:
Online Access:https://www.mdpi.com/1999-4915/13/7/1390