The cardiac glycoside convallatoxin inhibits the growth of colorectal cancer cells in a p53-independent manner
Cardiac glycosides are plant-derived molecules that have shown antiproliferative properties against cancer cells, though the mechanism of action is not completely understood. We show that one cardiac glycoside, convallatoxin, presents antiproliferative effects against colorectal cancer cells in cult...
Main Authors: | Sarah E. Anderson, Christopher E. Barton |
---|---|
Format: | Article |
Language: | English |
Published: |
Elsevier
2017-12-01
|
Series: | Molecular Genetics and Metabolism Reports |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2214426917301131 |
Similar Items
-
Convallatoxin induces HaCaT cell necroptosis and ameliorates skin lesions in psoriasis-like mouse models
by: Bo-Wen Jiang, et al.
Published: (2020-01-01) -
Convallatoxin Promotes M2 Macrophage Polarization to Attenuate Atherosclerosis Through PPARγ-Integrin αvβ5 Signaling Pathway
by: Zhang Y, et al.
Published: (2021-02-01) -
Zebrafish BID Exerts an Antibacterial Role by Negatively Regulating p53, but in a Caspase-8-Independent Manner
by: Zhitao Qi, et al.
Published: (2021-08-01) -
Effect of p53-targeted small molecular reactivator of p53 and induction of tumor apoptosis (RITA) combined with temozolomide (TMZ) on the glioma cell growth in vitro
by: Tao Jiang, et al.
Published: (2017-05-01) -
The Role of P53 in Oral Cancer - A Review
by: C Poornima, et al.
Published: (2005-01-01)