Modern and traditional approaches combined into an effective gray-box mathematical model of full-blood acid-base

Abstract Background The acidity of human body fluids, expressed by the pH, is physiologically regulated in a narrow range, which is required for the proper function of cellular metabolism. Acid-base disorders are common especially in intensive care, and the acid-base status is one of the vital clini...

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Bibliographic Details
Main Authors: Filip Ježek, Jiří Kofránek
Format: Article
Language:English
Published: BMC 2018-09-01
Series:Theoretical Biology and Medical Modelling
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12976-018-0086-9