Potential Therapeutic Features of Human Amniotic Mesenchymal Stem Cells in Multiple Sclerosis: Immunomodulation, Inflammation Suppression, Angiogenesis Promotion, Oxidative Stress Inhibition, Neurogenesis Induction, MMPs Regulation, and Remyelination Stimulation

Potential Therapeutic Features of Human Amniotic Mesenchymal Stem Cells in Multiple Sclerosis: Immunomodulation, Inflammation Suppression, Angiogenesis Promotion, Oxidative Stress Inhibition, Neurogenesis Induction, MMPs Regulation, and Remyelination Stimulation

Multiple sclerosis (MS) is an inflammatory and degenerative disorder of the central nervous system with unknown etiology. It is accompanied by demyelination of the nerves during immunological processes in the presence of oxidative stress, hypoxia, cerebral hypo-perfusion, and dysregulation in matrix...

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Bibliographic Details
Main Authors: Mohsen Abbasi-Kangevari, Seyyed-Hadi Ghamari, Fahimeh Safaeinejad, Soheyl Bahrami, Hassan Niknejad
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-02-01
Series:Frontiers in Immunology
Subjects:
angiogenesis
anti-inflammation
antioxidant
amniotic membrane
mesenchymal stem cell
multiple sclerosis
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.00238/full

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