Postnatal survival of mice with maternal duplication of distal chromosome 7 induced by a Igf2/H19 imprinting control region lacking insulator function.
The misexpressed imprinted genes causing developmental failure of mouse parthenogenones are poorly defined. To obtain further insight, we investigated misexpressions that could cause the pronounced growth deficiency and death of fetuses with maternal duplication of distal chromosome (Chr) 7 (MatDup....
Main Authors: | Li Han, Piroska E Szabó, Jeffrey R Mann |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2010-01-01
|
Series: | PLoS Genetics |
Online Access: | http://europepmc.org/articles/PMC2794364?pdf=render |
Similar Items
-
More than Insulator: Multiple Roles of CTCF at the H19-Igf2 Imprinted Domain
by: Purnima eSingh, et al.
Published: (2012-10-01) -
Complete biallelic insulation at the H19/Igf2 imprinting control region position results in fetal growth retardation and perinatal lethality.
by: Dong-Hoon Lee, et al.
Published: (2010-09-01) -
Placental phenotypes associated with abnormal genomic imprinting on distal mouse chromosome 7
by: Oh-McGinnis, Rosemary
Published: (2011) -
Placental phenotypes associated with abnormal genomic imprinting on distal mouse chromosome 7
by: Oh-McGinnis, Rosemary
Published: (2011) -
Placental phenotypes associated with abnormal genomic imprinting on distal mouse chromosome 7
by: Oh-McGinnis, Rosemary
Published: (2011)