A Randomized, Triple-blind Placebo-controlled Trial to Determine the Effect of Saffron on the Serum Levels of MMP-9 and TIMP-1 in Patients with Multiple Sclerosis

A Randomized, Triple-blind Placebo-controlled Trial to Determine the Effect of Saffron on the Serum Levels of MMP-9 and TIMP-1 in Patients with Multiple Sclerosis

Matrix metalloproteinases (MMP)-9 facilitates the migration of T-cells to central nervous system (CNS), while tissue inhibitor of metalloproteinases-1(TIMP-1) inhibits the function of MMP-9. This study aimed to determine the appropriate treatment option for multiple sclerosis (MS). Forty-three rela...

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Bibliographic Details
Main Authors: Fatemeh Ghasemi Sakha, Amirreza Azimi Saeen, Seyed Mohammad Moazzeni, Farnaz Etesam, Gholamhassan Vaezi
Format: Article
Language:English
Published: Tehran University of Medical Sciences 2020-06-01
Series:Iranian Journal of Allergy, Asthma and Immunology
Subjects:
Matrix metalloproteinase 9
Multiple sclerosis
Saffron
Tissue inhibitor of metalloproteinases-1
Online Access:https://ijaai.tums.ac.ir/index.php/ijaai/article/view/2008

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