Interferon-γ Mediated Pathways And Mitogen Stimulated Proliferation During And After An Acute Infection

Interferon-γ Mediated Pathways And Mitogen Stimulated Proliferation During And After An Acute Infection

Background: Interferon-γ (IFN- γ) regulates the degradation of tryptophan to kynurenine via induction of indoleamine- 2,3-dioxygenase (IDO). Local tryptophan depletion and accumulation of toxic metabolites might impair the proliferative capacity of lymphocytes. The aim of this study was to assess th...

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Bibliographic Details
Main Authors: Knoll Miriam, Fuchs Dietmar, Weiss Guenter, Bellmann-Weiler Rosa, Kovrlija Bojana, Kurz Katharina
Format: Article
Language:English
Published: De Gruyter 2018-05-01
Series:Pteridines
Subjects:
neopterin
bacterial infection
proliferative response
Online Access:https://doi.org/10.1515/pteridines-2018-0005

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