Epstein Barr virus detection in cervical samples of women living with human immunodeficiency virus

• Main Authors: Ledy H.S. Oliveira, Larissa S. Santos, Fernanda G. Nogueira
• Format: Article
• Language: English
• Published: Universidade de São Paulo 2011-08-01
• Series: Revista do Instituto de Medicina Tropical de São Paulo
• Subjects: Epstein Barr Virus; Cervical smears; Human immunodeficiency virus
• Online Access: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0036-46652011000400011&lng=en&tlng=en

Epstein Barr Virus (EBV) is transmitted commonly by saliva, but it has been found in genital secretions, which suggests sexual transmission and led researchers to connect EBV and cervical neoplasia. People living with human immunodeficiency virus (HIV) are reported to be at high risk of acquiring genital infections and cervical lesions. To verify the presence of EBV in the genital tract and/or it could affect cervical changes, we analyzed cervical smears from 85 HIV seropositive women for EBV DNA determination. EBV was only detected in two (2.3%) samples. The present study provides neither evidence for EBV as sexually transmitted infection nor discards this possibility.