The Role of the Liver-Specific microRNA, miRNA-122 in the HCV Replication Cycle

The Role of the Liver-Specific microRNA, miRNA-122 in the HCV Replication Cycle

Hepatitis C virus (HCV) replication requires annealing of a liver specific microRNA, miR-122 to 2 sites on 5’ untranslated region (UTR). While, microRNAs downregulate gene expression by binding to the 3’ untranslated region of the target mRNA, in this case, the microRNA anneals to the 5’UTR of the v...

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Bibliographic Details
Main Authors: Rasika D. Kunden, Juveriya Q. Khan, Sarah Ghezelbash, Joyce A. Wilson
Format: Article
Language:English
Published: MDPI AG 2020-08-01
Series:International Journal of Molecular Sciences
Subjects:
hepatitis C virus 1
microRNA 2
miR-122 3
replication 4
translation 5
RNA stabilization 6
Online Access:https://www.mdpi.com/1422-0067/21/16/5677

Internet

https://www.mdpi.com/1422-0067/21/16/5677

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